The easy choice for your lab
1mDa
1 mDa mass accuracy at any mass
1 mDa mass accuracy at any mass
£5000
Save £5000 year-1 on LC solvents and consumables
Save £5000 year-1 on LC solvents and consumables
72 HRS
Upgrade an existing instrument in-situ in only three days
Upgrade an existing instrument in-situ in only three days
We are Verdel instruments, a company devoted to bringing multi-dimensional mass spectrometry to time of flight mass spectrometers. At Verdel, we have developed total correlation mass spectrometry (TOC-MS), a new methodology that puts mass spectrometry first to generate MS/MS data for every analyte in a complex mixture.
Testimonials
See how it works
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The Verdel mass spec upgrade kit
Verdel instruments have developed total correlation (TOC) mass spectrometry, which works by controlling how precursor ions are fragmented using stored waveform ion radius modulation (SWIM). SWIM effectively allows us to separate all ions by their mass to charge ratio, which causes products and precursors to be intrinsically linked including products originating from multiple precursors.
TOC mass spectrometry can be added to any quadrupole-time of flight instrument using a Verdel upgrade kit. The upgrade can be performed in-situ, is completely reversible and can include additional modifications to allow users to perform ultraviolet photodissociation.
Our data
The final TOC mass spectrometry data set can be plotted in three dimensions. As demonstrated in the “see how it works” video above, the x-axis contains high resolution data from the time of flight instrument. The y-axis shows the “precursor mass”, which is determined by the interaction of our precursor ions with the applied SWIM pulses. The z-axis is the signal intensity as measured by the time of flight.
When analysing data we often plot the results as a contour as shown in the image on the right. From the contour plot we can extract out traditional, two dimensional mass spectra, which will show all of the products associated with a specified precursor or vice-versa. In this contour we can see several key TOC mass spectrometry features, such as the precursor line and some clear fragment lines.
Innovating
the future of
mass spectrometers
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